PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
November 21, 2025Scientific ReportsOpen Access

Physical activity modifies the association between ambient air pollution and comorbid depression and disability in activities of daily living

View Full Paper
Ask AI
Bookmark
Share

Authors

YCYuquan ChenYYYan-Wei YouJHJiarong He

Discussion

Loading...

Member takes

Overview

Observational analysis shows ambient air pollution increases risk of depression and disability, but physical activity mitigates these effects.

Key Points

  • To explore the effects of physical activity on the risk of depression and disability associated with air pollution.
  • Cohort study of 11,875 adults aged 45 and older from China.
  • Analyzed health outcomes using time-varying Cox proportional hazards regression.
  • Adjusted for demographic, socioeconomic, and health-related factors.
  • 18.8% of participants developed depression over a median follow-up of 7 years.
  • 1.8% developed ADL disability, and 1.5% developed comorbidity.
  • Physical activity reduced comorbidity risk by 10.2% for PM2.5 and 6.1% for PM10.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/6924e3f8c0ce034ddc34f279https://doi.org/10.1038/s41598-025-25347-z
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between air pollution exposure, physical activity, and risk for cardiometabolic multimorbidity incidence: a cohort study from China2026
  2. 2Air pollution and cognitive function: the potential protective effect of physical activity2025
  3. 3Air pollution and cognitive function: the potential protective effect of physical activity2025
  4. 4Air Pollution and the Progression of Physical Function Limitations and Disability in Aging Adults2026
  5. 5Objectively measured the impact of ambient air pollution on physical activity for older adults2024 · 11 citations