Selective retina therapy for central serous chorioretinopathy with focal choroidal excavation: a retrospective case series of six eyes

Background We evaluated the clinical outcomes of selective retina therapy (SRT) in patients with central serous chorioretinopathy (CSC) who had nonconforming focal choroidal excavations (FCEs). Methods Among the 204 patients with chronic CSC who underwent SRT between June 2023 and February 2025, six patients (2.9%) with nonconforming FCEs were analyzed. Using a Q-switched Nd: YLF 527-nm laser device, SRT was applied at leaking points or in leakage areas according to the features observed on fundus fluorescein angiography. The mean best-corrected visual acuity (BCVA), central foveal thickness (CFT), subfoveal choroidal thickness height, and mean deviation (MD) of retinal sensitivity were measured during the follow-up period. Results Among the six patients, five patients showed complete subretinal fluid (SRF) resolution, while one patient demonstrated minimal persistent SRF during the follow-up period. Four patients showed an improvement in BCVA, while BCVA remained unchanged in the other two patients. All patients showed improvement in the MD of retinal sensitivity during the follow-up period. Among the six patients, two patients showed complete SRF resolution after a single session of SRT, while the other four patients required multiple SRT sessions. No SRT-related adverse events were observed during the follow-up period. Conclusion SRT produced favorable outcomes in the treatment of patients with CSC and nonconforming FCEs.