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This research investigates the presence and characteristics of microstates in rats' EEG, bridging the gap between human and animal studies.

November 21, 2025Translational PsychiatryOpen Access

Microstate in rats’ EEG: a proof of concept study

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This research investigates the presence and characteristics of microstates in rats' EEG, bridging the gap between human and animal studies.
Collected EEG data from rats using a superficial electrode system corresponding to human 10-20 system.
Characterized microstates in EEGs and calculated variability measures including explained variance, mean temporal coverage, and average duration.
Used source localisation techniques to identify brain regions involved in microstate dynamics.
Detected five microstate EEG maps explaining 71% of variance in the dataset.
Mean temporal coverage was 0.2 seconds, and average microstate duration was 0.26 seconds, comparable to humans.
Identified associations of microstates with the cingulate cortex, precuneus, and insula.

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Proof of concept study identifies microstates in rats' EEG, suggesting biomarkers for brain diseases.

Piorecka et al. (2025) studied this question.

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