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November 21, 2025Cutaneous and Ocular Toxicology

Analysis of clinical characteristics of tislelizumab-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in the Chinese population: a systematic review

Xiuling Wen Wei-En Li Qinghua Zhang

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Key Points

To analyze the clinical characteristics of Stevens-Johnson syndrome and toxic epidermal necrolysis induced by tislelizumab in the Chinese population.
Conducted a systematic review of clinical cases of SJS/TEN related to tislelizumab in Chinese patients.
Evaluated the timing of occurrence following treatment and clinical presentations.
Identified that tislelizumab-induced SJS/TEN primarily occurs days to months post-treatment.
Emphasized the need for improved evaluation and monitoring of early cutaneous adverse reactions.

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Implication

Systematic review reveals SJS/TEN related to tislelizumab occurs after treatment, suggesting need for careful monitoring.

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Cite This Study

Wen et al. (2025) studied this question.

synapsesocial.com/papers/6924e3ffc0ce034ddc34f60e https://doi.org/10.1080/15569527.2025.2588769

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Analysis of adverse drug reactions in 507 cases of Tislelizumab: A real-world retrospective study based on data from Guangxi, China.2025
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