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November 21, 2025Parasites & VectorsOpen Access

Mutation in the knockdown resistance gene and population genetic structure in Culex tritaeniorhynchus from Guizhou Province

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Authors

WLWeiyi LiZLZhihao LiuXTXiao-Min Tang

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Overview

Analysis reveals genetic diversity and cryptic species in Culex tritaeniorhynchus populations, suggesting implications for pest control efforts.

Key Points

  • This study investigates the genetic diversity and structure of Culex tritaeniorhynchus in Guizhou Province, focusing on the knockdown resistance gene.
  • Collected 365 Culex tritaeniorhynchus mosquitoes from ten geographic populations in Guizhou Province.
  • Analyzed the kdr gene mutation and mtDNA–COI gene using PCR amplification and sequencing.
  • Constructed haplotype network diagrams and phylogenetic trees to assess genetic relationships.
  • Detected the L1014F mutation in the kdr gene with resistance allele frequencies ranging from 0% to 8.8%.
  • Identified high haplotype diversity (Hd = 0.989) and low nucleotide diversity (π = 0.023).
  • Found low genetic differentiation among populations and high gene flow, indicating frequent genetic exchange.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/6924e405c0ce034ddc34f76bhttps://doi.org/10.1186/s13071-025-07071-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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