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November 21, 2025NutrientsOpen Access

Clinical Significance of Phase Angle for Assessing Quality of Life and Prognosis in Hemodialysis Patients

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Authors

NYNorihito YoshidaTTTatsuki TanakaYSYusuke Suzuki

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Overview

Multicenter study shows phase angle correlates with nutritional markers and health-related quality of life in hemodialysis patients, suggesting its use as a biomarker.

Key Points

  • To investigate the associations between phase angle, quality of life, and prognosis in hemodialysis patients.
  • Multicenter cross-sectional study
  • Involved 319 hemodialysis patients stratified by sex-specific phase angle quartiles
  • Evaluated health-related quality of life using SF-36 and KDQOL-SF™
  • Conducted multivariable linear regression and Kaplan–Meier analysis
  • Higher phase angle linked to better nutritional parameters such as hemoglobin and albumin
  • Phase angle positively correlated with muscle mass and intracellular water
  • Independent association of phase angle with physical quality of life domains
  • Kaplan–Meier findings indicated lower survival rates in the lowest phase angle quartile
  • Identified phase angle cutoffs for predicting mortality based on sex

Cite This Study

Yoshida et al. (2025) studied this question.

synapsesocial.com/papers/6924e405c0ce034ddc34f8afhttps://doi.org/10.3390/nu17233631
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phase angle as a predictor of nutritional status and quality of life in hemodialysis patients2026 · 1 citations
  2. 2Influence of albumin and phase angle on the survival of patients with chronic kidney disease on hemodialysis: a prospective study2025 · 1 citations
  3. 3Association of Phase Angle with Body Composition in Hemodialysis Patients: A Case–Control Study2025
  4. 4Body composition changes and influencing factors of phase angle in maintenance hemodialysis patients with diabetic nephropathy2025 · 1 citations
  5. 5Associations between bioelectrical impedance analysis‐derived phase angle, protein‐energy wasting and all‐cause mortality in older patients undergoing haemodialysis2024 · 6 citations