Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI

Tao Ouyang; Huang Zhenghui; Shuxing Wei; Jun Yang; Andreas Voskrebenzev; Jens Vogel-Claussen; Shubin Guo; Qi Yang

doi:10.1016/j.compbiomed.2025.111316

November 20, 2025Computers in Biology and MedicineOpen Access

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI

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Key Points

This research aims to assess pulmonary perfusion and ventilation defects in long COVID over a one-year period.
Longitudinal study design
Evaluated pulmonary perfusion and ventilation defects
Used phase-resolved functional lung MRI (PREFUL)
Involved patients up to 12 months post SARS-CoV-2 infection.
Pulmonary perfusion impairment persists for 12 months post infection
Severe perfusion defects during acute phase associated with long COVID risk.

Implication

Longitudinal assessment reveals severe pulmonary perfusion defects in patients with long COVID, suggesting lasting impacts of SARS-CoV-2 infection.

Abstract

Pulmonary perfusion impairment persists up to 12 months following SARS-CoV-2 infection. Severe perfusion defects during acute phase are a risk factor for the development of long COVID.

Discussion

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Cite This Study

Ouyang et al. (2025) studied this question.

synapsesocial.com/papers/6924f07ac0ce034ddc34ff93 https://doi.org/10.1016/j.compbiomed.2025.111316

View Full Paper

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Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI

Key Points

Implication

Abstract

Discussion

Cite This Study

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI

Key Points

Implication

Abstract

Discussion

Cite This Study

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