What question did this study set out to answer?

To highlight the diagnostic challenges associated with bone marrow evaluations and the importance of adequate sampling.

November 20, 2025Frontiers in OncologyOpen Access

Case Report: Pitfalls in bone marrow evaluation: importance of adequate bone marrow sampling

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Case report reveals diagnostic errors related to sampling in bone marrow assessments, indicating the need for improved techniques.

To highlight the diagnostic challenges associated with bone marrow evaluations and the importance of adequate sampling.
Case report analysis of three challenging diagnostic cases
Review of the literature regarding bone marrow sampling pitfalls
Discussion of ancillary techniques supporting diagnosis
Identified common sampling errors contributing to diagnostic failures
Emphasized the role of immunohistochemistry in differentiation
Outlined strategies to mitigate diagnostic errors in bone marrow evaluations

Ghezavati et al. (2025) studied this question.

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