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November 20, 2025International Journal of Behavioral Nutrition and Physical ActivityOpen Access

Non-linear dose-response association between physical activity and mental health in adolescents: a prospective cohort study based on SEARCH

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Authors

YZYue ZhangZWZhuo WangRZRan Zhang

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Overview

Prospective cohort study reveals physical activity improves mental health in adolescents, highlighting cross-sectional associations.

Key Points

  • To examine the association between physical activity and mental health in adolescents and identify optimal activity levels.
  • Analyzed data from 6,991 adolescents in Jiangsu, China
  • Mental health measured using the Strengths and Difficulties Questionnaire
  • Categorized physical activity as moderate or vigorous intensity based on self-reports
  • Conducted cross-sectional and longitudinal analyses while controlling for confounders
  • 1,265 adolescents (18.1%) had mental health issues at baseline
  • Significant non-linear associations between physical activity and mental health problems were observed
  • 30-59 min of moderate physical activity daily linked to a 56.4% reduction in mental health issues
  • Up to 29 min of vigorous physical activity linked to a 49.2% reduction in mental health issues

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/6924f084c0ce034ddc350481https://doi.org/10.1186/s12966-025-01848-y
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Associations between physical activity and mental well-being among adolescents in the Danish health behaviour in school-aged children study2026
  2. 2Longitudinal associations between physical activity intensity and mental health problems in overweight/obese youth2025 · 2 citations
  3. 3Impact of physical activity on symptoms of depression and anxiety in adolescents during the COVID-19 pandemic2025 · 4 citations
  4. 4Physical activity and mental health in children and adolescents during and after the COVID-19 pandemic: findings from the six-wave German COPSY study2026 · 2 citations
  5. 5Multidimensional Impact of Regular Physical Activity on Adolescent Mental Health, Integrating Neurobiological and Psychosocial Mechanisms2024 · 5 citations