Case report reveals corneal ulceration from cranial nerve paralysis due to actinomycosis, suggesting urgent ophthalmological intervention.
Background Polyneuritis cranialis is a rare condition than can be caused by various diseases. We report the first case of multiple cranial nerve paralysis resulting in neurotrophic keratopathy with corneal ulceration as a sequel of polyneuritis cranialis due to actinomycosis. Case presentation An 84-year-old German woman developed corneal ulceration with a high risk of perforation because of neurotrophic keratopathy due to polyneuritis cranialis. Actinomycosis of a wisdom tooth causing polyneuritis cranialis was detected on computed tomography and magnetic resonance imaging and was treated with systemic antibiotics. Penetrating keratoplasty with simultaneous amniotic membrane transplantation was performed successfully after conservative treatment failure. Conclusions To the best of our knowledge, we report on the first case of multiple cranial nerve failure due to actinomycosis and requiring ophthalmological intervention.
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Welzel et al. (2025) studied this question.
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