Prospective study shows biomarkers improve imaging accuracy in blunt head trauma, indicating better clinical decision-making.
GFAP and UCH-L1 are highly sensitive and specific biomarkers for early ICH detection in blunt head trauma. Their combined use may enhance triage accuracy, reduce unnecessary imaging, and support rapid clinical decision-making in emergency settings. Larger multicenter studies are warranted to validate these findings and standardize cut-off values.
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Bilgin et al. (2025) studied this question.
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