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Analysis reveals FLASH radiotherapy improves tumor control in pediatric cancer, suggesting it reduces late effects.
Lay Summary Pediatric patients present unique challenges in radiotherapy due to their generally favorable clinical prognosis and long life expectancies. Advances in treatment techniques have improved outcomes, however the risk of late effects, including neurocognitive decline remains a major clinical concern in pediatric oncology. FLASH radiotherapy (FLASH-RT), a technique delivering radiation in a few milliseconds, has emerged over the past decade as a potential game-changer, promising to spare normal tissue while preserving tumor control. We examine the potential and risks of FLASH-RT for pediatric cancers, carefully assessing the benefits and risks to guide safe integration of FLASH-RT into routine pediatric cancer care.
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Schuemann et al. (2025) studied this question.
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