Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia

Q: What type of study is this?

This is a Pre-Registered Trial study.

Sarah E. Cusick; Ezekiel Mupere; Paul Bangirana; Reagan I. Baluku; Maria Kroupina; Carol L. Cheatham; Jeffrey R. Wozniak; Michael K. Georgieff

doi:10.1186/s13063-025-09246-2

November 19, 2025TrialsOpen Access

Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia

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Key Points

To evaluate the effects of choline supplementation on learning and memory deficits in infants with iron deficiency anemia.
Randomized, placebo-controlled trial design
Participants are Ugandan infants with iron deficiency anemia
Intervention includes supplemental choline and a placebo control group
Anticipated improvements in learning and memory outcomes with choline supplementation
Potential prevention of cognitive deficits associated with early-life iron deficiency

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Implication

Randomized trial examines choline treatment for learning deficits in Ugandan infants with iron deficiency anemia, indicating potential for improved cognitive outcomes.

Abstract

Clinical trials.gov NCT06527391. Registered on 24 July 2024.

Discussion

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Cite This Study

Cusick et al. (2025) studied this question.

synapsesocial.com/papers/6924fed1c0ce034ddc350d90 https://doi.org/10.1186/s13063-025-09246-2

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Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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