Case study reveals marked uptake of 99mTc-ethyl cysteinate dimer in parotid gland oncocytoma, suggesting mitochondrial activity involvement.
A 90-year-old man underwent SPECT with 99m Tc-ethyl cysteinate dimer (ECD) SPECT due to a 2-week history of aphasia and fever. 99m Tc ECD is a radiopharmaceutical that reflects cerebral blood flow. We present a case of parotid gland oncocytoma exhibiting marked ECD uptake in a brain SPECT scan. This finding suggests the certain extracerebral tumors may retain ECD due to intracellular mechanisms, potentially related to mitochondrial activity.
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Amano et al. (2025) studied this question.
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