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November 18, 2025Clinical and Experimental MedicineOpen Access

LncRNA SNHG11 expression in acute myeloid leukemia patients and its relationship with the biology of acute myeloid leukemia cells

Ke Sun Jing Zhou Hanbing Yao Peng Jiao Rui Zhang Gang-Feng Wang

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Key Points

This research aims to explore the role of LncRNA SNHG11 in acute myeloid leukemia (AML) and its implications on cell biology.
Analyzed SNHG11 expression in AML patients and healthy controls.
Assessed its diagnostic capability for AML.
Investigated the relationship between SNHG11 and miR-122-5p.
Identified SNHG11 expression as a potential biomarker for diagnosing AML.
Found a correlation between high SNHG11 levels and poor prognosis in AML patients.
Demonstrated an impact of SNHG11 on the biology of AML cells through miR-122-5p.

Implication

Findings reveal acute myeloid leukemia expression linked to poor prognosis in patients, indicating cell biology implications.

Abstract

SNHG11 could diagnose AML from healthy controls and related to poor prognosis of AML patients. SNHG11 could impact cell biology through miR-122-5p.

Discussion

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Cite This Study

Sun et al. (2025) studied this question.

synapsesocial.com/papers/6924fee6c0ce034ddc35175c https://doi.org/10.1007/s10238-025-01923-5

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