Association between changes in systolic blood pressure and the incidence of diabetes mellitus: a retrospective study based on the Korean National Health Screening Cohort

The median follow-up was 14.3 years, and 26,352 patients with diabetes were identified. Compared to those with no change in SBP, the adjusted HRs for decrease and increase among males were 1.06 (95% CI, 1.02-1.10) and 1.10 (95% CI, 1.06-1.14), and 1.06 (95% CI, 1.00-1.12) and 1.08 (95% CI, 1.02-1.13) for females, respectively. After stratifying data according to SBP at baseline, the HRs for decrease in males and females were as follows: normotensive group, 1.16 (95% CI, 1.08-1.24) and 1.11 (95% CI, 1.02-1.21); and prehypertensive group, 1.14 (95% CI, 1.09-1.20) and 1.19 (95% CI, 1.10-1.29), respectively. Conclusion: Changes in SBP were associated with a risk for diabetes.