Genome analysis shows glycosylation of steroidal saponins in Dioscorea nipponica, suggesting convergent evolution among UGT families.
The UGT73 subfamily in Dioscorea nipponica exhibits remarkable catalytic diversity in glycosylation of steroidal saponins. Notably, DnU26 from the UGT73 subfamily and members of the phylogenetically distant UGT91 family independently evolved identical catalytic functions, revealing convergent evolution and the remarkable flexibility of plant glycosyltransferases in generating metabolic diversity.
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Wang et al. (2025) studied this question.
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