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Case analysis reveals histopathological examination is critical for diagnosing localized nodular amyloidosis, suggesting early identification may prevent systemic issues.
Primary Localized Cutaneous Nodular Amyloidosis (PLCNA) can rarely present on the face and may mimic more common dermatoses. In such atypical cases, especially in resource‐limited settings where confirmatory tests like Congo Red staining are unavailable, histopathological examination is crucial for diagnosis. Early recognition is vital for proper management and monitoring for potential systemic involvement.
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Shah et al. (2025) studied this question.
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