Observational data shows improved survival in colon cancer with unresectable liver metastases, suggesting tumor resection may be beneficial.
Primary tumor resection in patients with colon cancer and unresectable liver-only metastases is independently associated with improved survival. These findings support considering surgical intervention of the primary tumor as part of a comprehensive treatment strategy, although prospective studies are warranted to confirm these results.
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Ma et al. (2025) studied this question.
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