Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome

Maria Rossello-Gelabert; Kevin Las Heras; Ainhoa Gonzalez‐Pujana; Manoli IGARTÚA; Edorta Santos Vizcaino; Rosa Maria Hernandez

doi:10.1186/s13287-025-04775-8

November 17, 2025Stem Cell Research & TherapyOpen Access

Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome

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Key Points

To investigate the potential of iHF-MSCs for the production of therapeutic secretome.
Development of immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs)
Assessment of the secretome production capabilities of iHF-MSCs
iHF-MSCs provide a robust platform for therapeutic secretome production
Potential application in cell-free immunomodulatory and regenerative therapies

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Implication

Findings position iHF-MSCs for consistent production of therapeutic secretome, suggesting new immunomodulatory approaches.

Abstract

These results position iHF-MSCs as a robust and scalable platform for consistent production of therapeutic secretome, paving the way for innovative, cell-free immunomodulatory and regenerative therapies.

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Cite This Study

Rossello-Gelabert et al. (2025) studied this question.

synapsesocial.com/papers/692509e8c0ce034ddc3526e2 https://doi.org/10.1186/s13287-025-04775-8

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Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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