Longitudinal studies show hemodialysis impacts beta-2 microglobulin in children, suggesting optimization strategies are needed.
Synthetic-based high-flux dialyzers were associated with improved beta-2 MG clearance in pediatric HD patients, though pre-HD levels were comparable across membrane types. Further longitudinal studies are warranted to determine the clinical significance of beta-2 MG reduction and guide dialysis optimization in children.
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Sari et al. (2025) studied this question.
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