Cohort study finds higher discontinuation of buprenorphine compared to methadone during and after pregnancy, indicating implications for opioid use disorder treatment.
Women with opioid use disorder (OUD) who initiated buprenorphine treatment early in pregnancy discontinued the medication at a higher rate than women who initiated methadone, a cohort study based on public insurance data found. Discontinuation rates for buprenorphine also were higher than those for methadone in the period one year postpartum.
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