Randomised trial shows N‐acetylcysteine has no significant effect on PTSD and alcohol outcomes compared to placebo.
The largest trial to date of the antioxidant N‐acetylcysteine for the treatment of co‐occurring post‐traumatic stress disorder (PTSD) and alcohol use disorder (AUD) showed no significant difference from placebo on numerous PTSD‐ and drinking‐related outcomes. Both the N‐acetylcysteine and placebo groups showed marked improvement on most studied measures.
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