What question did this study set out to answer?

To evaluate retention rates and patient outcomes in baricitinib-treated patients with rheumatoid arthritis in Japan.

November 17, 2025Modern Rheumatology

Retention of baricitinib-treated patients with rheumatoid arthritis in Japan: Interim results from a prospective observational cohort study

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Authors

YKYuko Kaneko CWChao-Chen Wang NTNaoto Tsujimoto

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Implication

Prospective observational study shows 70% retention in baricitinib-treated rheumatoid arthritis patients, indicating effective outcomes and predictors of treatment discontinuation.

Key Points

To evaluate retention rates and patient outcomes in baricitinib-treated patients with rheumatoid arthritis in Japan.
Ongoing multi-centre, prospective observational study
Included adults ≥20 years old with rheumatoid arthritis
Evaluated retention rate and effectiveness for 12 months
Utilized Random Forest analysis to assess treatment discontinuation predictors.
12-month retention rate was 70.2%
12-month remission rates were 35.3%, 41.1%, and 79.6% based on different disease activity indices
Mean improvement in patient-reported outcomes included -33.8 in physician assessment and -18.3 in patient assessment

Cite This Study

Kaneko et al. (2025) studied this question.

synapsesocial.com/papers/692509ffc0ce034ddc353111 https://doi.org/10.1093/mr/roaf113

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Implication

Prospective observational study shows 70% retention in baricitinib-treated rheumatoid arthritis patients, indicating effective outcomes and predictors of treatment discontinuation.

Retention of baricitinib-treated patients with rheumatoid arthritis in Japan: Interim results from a prospective observational cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

Retention of baricitinib-treated patients with rheumatoid arthritis in Japan: Interim results from a prospective observational cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

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