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November 14, 2025Open Access

Intracellular Ph as a Novel Prognostic Marker for Cancer Risk Assessment

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Authors

UAUmair Masood awan

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Implication

Observations suggest intracellular pH enhances cancer risk prediction, highlighting its role as a biomarker in cancer cells.

Key Points

  • To evaluate intracellular pH (pHi) as a novel prognostic marker for cancer risk assessment.
  • Investigated the relationship between pHi and cancer cell behavior.
  • Analyzed the effects of altered pHi on cell-cycle progression and enzyme activity.
  • Explored pH measurement techniques for reliable assessment.
  • Higher intracellular pH is associated with cancer cell proliferation and survival.
  • Altered pHi contributes to oncogenic transformation and invasion.
  • pHi measurement may improve early detection and risk stratification.

Cite This Study

Umair Masood awan (2025) studied this question.

synapsesocial.com/papers/692519b4c0ce034ddc354571https://doi.org/10.5281/zenodo.17605713
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1INTRACELLULAR PH AS A NOVEL PROGNOSTIC MARKER FOR CANCER RISK ASSESSMENT2025
  2. 2Intracellular pH differentially regulates transcription of metabolic and signaling pathways in normal epithelial cells2024 · 1 citations
  3. 3Imaging the transmembrane pH gradient in gliomas2024
  4. 4BPS2026 – The role of cancer-associated physicochemical changes for protein structure and aggregation2026
  5. 5Can pH can be a marker of hypoxia? Role of MRI CEST pH imaging in differentiating hypoxic from non-hypoxic tumors.2024