Combinatorial approach improves antitumor efficacy in solid tumors, suggesting immunotherapy may overcome immune resistance.
This study presents a synergistic immunotherapy platform that integrates NK reprogramming, CAR engineering, and tumor sensitization. The combinatorial approach significantly enhances antitumor efficacy in PDAC and offers a promising strategy for overcoming immune resistance in solid tumors.
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Kim et al. (2025) studied this question.
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