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November 13, 2025Frontiers in MedicineOpen Access

Optimizing myopia prediction in children and adolescents using machine learning: a multi-factorial risk assessment model

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Authors

YXYue XiWZWei ZhuWYWenjing Yan

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Overview

Cross-sectional analysis identifies behavioral and genetic factors influencing myopia risk in children, suggesting machine learning models can predict outcomes effectively.

Key Points

  • To evaluate the role of modifiable risk factors and machine learning in predicting myopia among children and adolescents.
  • Cross-sectional survey conducted in schools in China
  • Data split into training and testing sets
  • LASSO regression and multivariate logistic regression used for predictor identification
  • Ten machine learning algorithms tested for prediction accuracy
  • Model performance evaluated using accuracy, F1 score, and AUC.
  • Myopia prevalence was 25.12% among 2,086 children and adolescents
  • LightGBM achieved the best predictive performance (AUC = 0.738)
  • Key risk factors included parental myopia, physical activity, and only-child status.

Cite This Study

Xi et al. (2025) studied this question.

synapsesocial.com/papers/692523bbc0ce034ddc354926https://doi.org/10.3389/fmed.2025.1672432
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1School-level prediction and management of myopia in children and adolescents2025 · 6 citations
  2. 2Predicting onset of myopic refractive error in children using machine learning on routine pediatric eye examinations only2025
  3. 3Prediction of myopia onset and shift in premyopic school-aged children: a machine learning-based algorithm2025
  4. 4Predicting myopia risk using a machine learning model based on fundus imageomics2025
  5. 5Revolutionizing Pediatric Myopia Care: A Machine Learning Approach for Rapid and Accurate Pre-clinical Screening2026