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This research investigates the link between ambient air pollution exposure during pregnancy and the risk of early-onset breast cancer.

November 13, 2025Breast Cancer ResearchOpen Access

Exposure to ambient air pollution during pregnancy and risk of early-onset breast cancer

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Authors

JEJessica Edlund WWWendy Yi Ying Wu MGMalin Gustafsson

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Implication

Cohort study reveals increased breast cancer risk in women exposed to air pollution during pregnancy, suggesting environmental factors play a significant role.

Key Points

This research investigates the link between ambient air pollution exposure during pregnancy and the risk of early-onset breast cancer.
Analyzed data from a cohort of cancer-free women giving birth in Sweden from 1991 to 2015.
Modelled residential exposure to nitrogen dioxide, particulate matter <10 μm, and particulate matter <2.5 μm based on 2019 air pollution data.
Used Cox proportional hazards regression to estimate adjusted hazard ratios and confidence intervals for breast cancer risk.
Among 1,019,076 women, 12,085 were diagnosed with breast cancer, suggesting a notable incidence rate.
Higher risks were observed for exposure to PM coarse during the last pregnancy, with an HR of 1.12 per 5 μg/m3 increase.
Only invasive breast cancer was linked to air pollution exposure, excluding ductal carcinoma in situ.

Cite This Study

Edlund et al. (2025) studied this question.

synapsesocial.com/papers/692523c1c0ce034ddc354bcc https://doi.org/10.1186/s13058-025-02165-9

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Implication

Cohort study reveals increased breast cancer risk in women exposed to air pollution during pregnancy, suggesting environmental factors play a significant role.

Exposure to ambient air pollution during pregnancy and risk of early-onset breast cancer

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Implication

Key Points

Cite This Study

Exposure to ambient air pollution during pregnancy and risk of early-onset breast cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

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