November 13, 2025Frontiers in PediatricsOpen Access

Case Report: Mycoplasma pneumoniae-induced rash and mucositis (MIRM) in an 8-year-old girl: concise review of a challenging case.

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To discuss a case of Mycoplasma pneumoniae-induced rash and mucositis in an 8-year-old girl.
Case report detailing symptoms, laboratory testing, and treatment plan for an 8-year-old girl.
Laboratory confirmed M. pneumoniae infection via IgM antibody and DNA testing.
Initial treatment included azithromycin and methylprednisolone sodium succinate, followed by intravenous immunoglobulin.
Improvement in respiratory symptoms after initial treatment with azithromycin and MPSS.
Progressive rash developed after treatment with MPSS but resolved after administering IVIG.
Mucocutaneous manifestations resolved by hospital day 10, showcasing the effectiveness of multimodal therapy.

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Case report reveals mucositis linked to M. pneumoniae in a child, suggesting need for early multimodal therapy.

Li et al. (2025) studied this question.

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