What question did this study set out to answer?

This review aims to investigate the role of resident macrophages in intraperitoneal metastasis of gastric cancer and their potential as therapeutic targets.

November 13, 2025International Journal of SurgeryOpen Access

Intraperitoneal metastasis of gastric cancer: new insights on resident macrophages

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Authors

XYXianzhe Yu LWLei-bo Wang LZLingling Zhu

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Implication

This review explores therapeutic targets and outcomes linked to intraperitoneal metastasis in gastric cancer, highlighting combination therapies.

Key Points

This review aims to investigate the role of resident macrophages in intraperitoneal metastasis of gastric cancer and their potential as therapeutic targets.
Review of the immune microenvironment in gastric cancer peritoneal metastasis.
Discussion of resident macrophages and their pro-tumor characteristics.
Evaluation of emerging therapeutic strategies targeting macrophages.
Identified resident macrophages contribute to the immunosuppressive microenvironment in gastric cancer peritoneal metastasis.
Highlighted the role of macrophages in promoting chemotherapy resistance.
Discussed various therapeutic strategies, including HIPEC and macrophage repolarization, showing promise in improving outcomes.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/692523c6c0ce034ddc354f3b https://doi.org/10.1097/js9.0000000000003944

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Implication

This review explores therapeutic targets and outcomes linked to intraperitoneal metastasis in gastric cancer, highlighting combination therapies.

Intraperitoneal metastasis of gastric cancer: new insights on resident macrophages

Discussion

Member takes

Implication

Key Points

Cite This Study

Intraperitoneal metastasis of gastric cancer: new insights on resident macrophages

Discussion

Member takes

Implication

Key Points

Cite This Study

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