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November 12, 2025Frontiers in Public HealthOpen Access

Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040

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Authors

YHYali HanHCHui ChenHCHui Chen

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Overview

This analysis reveals increasing breast and ovarian cancer burdens in China, suggesting urgent intervention strategies.

Key Points

  • To identify and project trends in female cancers and their risk factors in China.
  • Analyzed incidence, prevalence, mortality, and DALY data from the Global Burden of Disease Study 2021.
  • Utilized estimated annual percentage change (EAPC) and age-period-cohort (APC) models for trend analysis.
  • Employed Bayesian APC model for projecting cancer burdens.
  • Breast cancer had the highest incidence and mortality in 2021, with rates doubling from 1990 to 2021.
  • Cervical cancer showed slight incidence increases but declining mortality and DALYs.
  • Projections indicate rising burdens for breast, uterine, and ovarian cancers by 2040.

Cite This Study

Han et al. (2025) studied this question.

synapsesocial.com/papers/692523cec0ce034ddc3552bdhttps://doi.org/10.3389/fpubh.2025.1629081
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Also Consider

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  1. 1Burden and temporal trends of female-specific cancers in China: A systematic analysis of the 2023 global burden of disease study2026 · 2 citations
  2. 2Evaluation of the breast cancer disease burden in China from 1990 to 2021: based on the Global Burden of Disease Study 20212025 · 1 citations
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  4. 4Trends of Female Breast Cancer Burden in China over 25 Years: A Join Point Regression and Age-Period-Cohort Analysis Based on the GBD (1997–2021)2025 · 3 citations
  5. 5Long-term trends and projections of ovarian cancer burden in China (1990 to 2040): an age-period-cohort analysis based on GBD 2021 data.2025 · 8 citations