What question did this study set out to answer?

This research aims to compare the performance of different insulin resistance indices in prediabetes and type 2 diabetes patients.

November 12, 2025Istanbul Medical JournalOpen Access

Evaluation of the Relationship Between Five Different Insulin Resistance Indices and Glycemic Control in Patients with Prediabetes and Type 2 Diabetes

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Authors

SASinem Aydin LDLevent Deniz ÖDÖzlem Demirelce

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Implication

This evaluation reveals glycemic control associations in prediabetes and type 2 diabetes, suggesting insulin resistance indices could enhance patient care.

Key Points

This research aims to compare the performance of different insulin resistance indices in prediabetes and type 2 diabetes patients.
Participants categorized by HbA1c levels according to American Diabetes Association criteria
Analysis of patient records for glucose, triglycerides, HDL-C, and insulin
Evaluation of HOMA-IR, QUICKI, TyG, and other indices
Receiver operating characteristic analysis to determine diagnostic performance
The non-regulated T2DM group exhibited higher HOMA-IR and TyG levels and lower QUICKI values
TyG and HOMA-IR showed positive correlation with HbA1c
TyG demonstrated the highest AUC of 0.749 for identifying HbA1c ≥5.70%
Indices including TyG and HOMA-IR were associated with HbA1c ≥5.70%, independent of demographics

Cite This Study

Aydin et al. (2025) studied this question.

synapsesocial.com/papers/692523d4c0ce034ddc35541f https://doi.org/10.4274/imj.galenos.2025.29498

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Implication

This evaluation reveals glycemic control associations in prediabetes and type 2 diabetes, suggesting insulin resistance indices could enhance patient care.

Evaluation of the Relationship Between Five Different Insulin Resistance Indices and Glycemic Control in Patients with Prediabetes and Type 2 Diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

Evaluation of the Relationship Between Five Different Insulin Resistance Indices and Glycemic Control in Patients with Prediabetes and Type 2 Diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

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