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This is a In Vitro Study study.

November 12, 2025Biomaterials AdvancesOpen Access

Development of novel organic/inorganic osteomimetic inks for 3D bioprinted in vitro bone models

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Bioinks enhanced stability in printed structures, facilitating 3D bioprinting for in vitro bone models.
Osteosarcoma Saos-2 cells proliferated in bioinks without cytotoxic effects over 14 days.
Rheological behavior of gelatin-based formulations was optimized for successful 3D printing.
Nanocrystals were incorporated to replicate the inorganic features of native bone tissue.

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In vitro analysis demonstrates stability properties in bioinks for osteosarcoma cells, highlighting potential in bone disease research.

Fischetti et al. (2025) studied this question.

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