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This study investigates the prevalence and risk factors associated with Hepatozoon canis in dogs from Tehran.

November 12, 2025BMC Veterinary ResearchOpen Access

Molecular identification and associated risk factors of Hepatozoon canis among dogs visiting veterinary clinics in Tehran, Iran

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Molecular analysis reveals prevalence of Hepatozoon canis in dogs, indicating significant risk factors in urban environments.

This study investigates the prevalence and risk factors associated with Hepatozoon canis in dogs from Tehran.
Blood samples were collected from dogs admitted to veterinary clinics.
PCR was used to test samples for Hepatozoon canis using the 18 S rRNA gene.
Data on demographics and clinical symptoms were also collected.
33 Hepatozoon-positive cases were identified from 170 samples, yielding a prevalence of 19.4%.
Higher prevalence noted in rural and suburban environments, especially in female dogs aged 1-13 years.
Common clinical signs included lymphadenomegaly, fever, and muscular pain.

Tamai et al. (2025) studied this question.

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