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November 12, 2025Clinical and Experimental NephrologyOpen Access

Acute kidney injury as a prognostic determinant in cardiogenic shock: a cohort study

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Authors

PBPriyanka BoettgerHPHenriette Preusse-SondermannJSJamschid Sedighi

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Overview

Cohort study shows renal replacement therapy use relates to high mortality in cardiogenic shock, suggesting urgent renoprotective strategies.

Key Points

  • The research aims to determine how acute kidney injury influences outcomes in cardiogenic shock after a myocardial infarction.
  • Retrospective analysis of 369 patients with infarct-related cardiogenic shock
  • Defined acute kidney injury using KDIGO criteria
  • Analyzed clinical, laboratory, and hemodynamic data
  • 42.8% of patients developed acute kidney injury, with significant correlations to age and prior chronic kidney disease
  • Mortality rate in AKI patients was notably high at 60.6% with renal replacement therapy used in 23.1% of these cases
  • Overall mortality in the cohort was 57.7%, higher among women

Cite This Study

Boettger et al. (2025) studied this question.

synapsesocial.com/papers/692523d4c0ce034ddc355651https://doi.org/10.1007/s10157-025-02787-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The heart-kidney connection: acute kidney injury in cardiogenic shock2025 · 1 citations
  2. 2Impact and predictors of acute kidney injury in cardiogenic shock following acute myocardial infarction2026
  3. 3Acute kidney injury in acute decompensated heart failure related cardiogenic shock: data from the Alt-Shock2 registry2024
  4. 4Early Versus Late-Onset Acute Kidney Injury in Cardiogenic Shock: Differential Prognostic Implications2025
  5. 5Acute kidney injury treated with renal replacement therapy and 5-year mortality after myocardial infarction-related cardiogenic shock: a nationwide population-based cohort study2015 · 79 citations