Gold(I)-catalysed cycloisomerisation leads to distinct indole structures, suggesting selectivity may guide diverse applications.
We report a regiodivergent gold(I)-catalysed cycloisomerisation of terminal 2-alkynyl anilines that affords either C2-o-tolylindoles via a [3,4]-sigmatropic rearrangement or C2/C3-benzylindoles via [1,2]-benzylic migration, where the selectivity is totally controlled by...
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García-Dueñas et al. (2025) studied this question.
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