The effects of MEP counts on intra- and intersession reliability of single-pulse TMS-induced MEPs in the wrist extensor muscle of healthy individuals

Hamed AlAnazi; Prue Morgan; Shapour Jaberzadeh

doi:10.1016/j.jneumeth.2025.110621

November 11, 2025Journal of Neuroscience MethodsOpen Access

The effects of MEP counts on intra- and intersession reliability of single-pulse TMS-induced MEPs in the wrist extensor muscle of healthy individuals

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Key Points

Highly reproducible amplitude measurements with fewer MEP counts in the wrist extensor muscle, showing a reliable method.
Averaging MEPs from the ECR results in lower variability, implying effective assessment using fewer blocks.
Assessments of MEP latency require more blocks for consistency, indicating the need for a precise approach.
Impacts reliable TMS protocols for evaluating muscle responses in clinical settings, requiring further validation.

Implication

Observational analysis reveals MEP amplitude yields high reproducibility in healthy individuals, suggesting optimal block use for reliability.

Abstract

This study suggests that averaging MEPs from the ECR yields highly reproducible amplitude measurements with few blocks, whereas MEP latency requires more blocks to achieve high inter-session reliability.

Discussion

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Cite This Study

AlAnazi et al. (2025) studied this question.

synapsesocial.com/papers/69252e9ec0ce034ddc356608 https://doi.org/10.1016/j.jneumeth.2025.110621

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The effects of MEP counts on intra- and intersession reliability of single-pulse TMS-induced MEPs in the wrist extensor muscle of healthy individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

The effects of MEP counts on intra- and intersession reliability of single-pulse TMS-induced MEPs in the wrist extensor muscle of healthy individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

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