The development of a nociceptor device shows enhanced plasticity and fatigue behaviors, suggesting applications in robotics and prosthetics.
Nociceptors, the body’s essential alarm system, detect harmful stimuli (mechanical, thermal, chemical) and trigger protective neural responses. Memristive devices offer a powerful platform for emulating such biological functions due to their ion-migration dynamics, which naturally replicate neural threshold behaviors and plasticity. While prior memristive artificial nociceptors have successfully mimicked key characteristics of A-MH I-type nociceptors (threshold activation, relaxation, allodynia, hyperalgesia), the implementation of A-MH II-type responses, such as subthreshold response, rapid active, adaption and fatigue behaviors, remains scarce despite its critical role in realistic biomimetics. Here, we develop a Pt/NbO x /Graphene memristive device-based nociceptor leveraging electron trapping/de-trapping dynamics. This device comprehensively emulates both A-MH I-type features and previously overlooked A-MH II-type properties. The successful dual-type nociceptor emulation demonstrates exceptional potential for constructing high-fidelity biomimetic systems in advanced robotics, prosthetics, and neuromorphic sensing.
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Dai et al. (2025) studied this question.
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