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This is a Meta-Analysis study (also classified as: Systematic Review).

Target trial emulation in hypertension research: a scoping review of current applications and methodological practices

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Causal inference using inverse probability weighting was a primary method in hypertension research.
About 50% of studies utilized inverse probability weighting for confounding adjustment, while 36% employed negative controls.
Observational analysis found inconsistencies in addressing time-varying confounders and handling loss to follow-up.
Future development in target trial emulation may enhance understanding of long-term outcomes and treatment effects.

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Scoping review identifies confounding adjustments and suggests improvements for causal inference in hypertension research.

Habibdoust et al. (2025) studied this question.

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