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November 10, 2025The Egyptian Journal of Radiology and Nuclear MedicineOpen Access

External validation of CT-based severity scoring systems to determine prognosis of pneumonia caused by COVID-19 virus: a multicentric cohort study

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Authors

HAHossein AfrakhtehMSMohammad Reza SasaniHVHossein Molavi Vardanjani

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Overview

Multicentric cohort study demonstrates robust prognostic model for pneumonia mortality in COVID-19 patients, indicating vital role of CT scoring.

Key Points

  • The central aim is to validate the effectiveness of CT scoring systems in predicting pneumonia prognosis in COVID-19 patients.
  • Retrospective cohort design with 566 COVID-19 patients
  • Evaluation of CT images using 15-, 20-, and 24-point scoring systems
  • Mortality outcomes assessed and analyzed using logistic regression
  • ROC curve analysis conducted for model performance evaluation.
  • Highest odd ratio for mortality linked to CT severity score
  • 20-score model displayed the best area under the ROC curve at 0.672
  • All models effectively distinguished between survivors and non-survivors (P ≤ .001).

Cite This Study

Afrakhteh et al. (2025) studied this question.

synapsesocial.com/papers/69253a24c0ce034ddc35739dhttps://doi.org/10.1186/s43055-025-01622-x
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