Chloroquine Enhances Mda-7- Induced Apoptosis via miR-7 and HSP70 Modulation in Glioblastoma.

Seyedeh Maliheh Babazadeh; Mohammad Reza Zolfaghari; Mohsen Zargar; Kazem baesi; Amir Ghaemi

doi:10.61186/ibj.5131

November 10, 2025

Chloroquine Enhances Mda-7- Induced Apoptosis via miR-7 and HSP70 Modulation in Glioblastoma.

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Key Points

To explore the synergistic effects of Chloroquine and Ad/Mda-7 on glioblastoma cells.
Used Ad/Mda-7 and Chloroquine treatments on U87 glioblastoma cells.
Analyzed apoptosis induction and cancer cell growth inhibition.
Chloroquine enhanced Mda-7 induced apoptosis.
The combination treatment significantly inhibited U87 cancer cell growth.

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Implication

Combined treatment of Chloroquine and Mda-7 reduces cancer cell growth in glioblastoma, indicating a new therapeutic strategy.

Abstract

Our findings indicate that the combination of Ad/Mda-7 and CQ synergistically could inhibit U87 cancer cell growth and could serve as a promising approach for treating human GBM.

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Cite This Study

Babazadeh et al. (2025) studied this question.

synapsesocial.com/papers/69253a29c0ce034ddc357682 https://doi.org/10.61186/ibj.5131

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Chloroquine Enhances Mda-7- Induced Apoptosis via miR-7 and HSP70 Modulation in Glioblastoma.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Chloroquine Enhances Mda-7- Induced Apoptosis via miR-7 and HSP70 Modulation in Glioblastoma.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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