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November 10, 2025Modern Rheumatology Case Reports

Lupus Podocytopathy as a First Renal Manifestation in Long-standing Systemic Lupus Erythematosus: A case report

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Authors

TTTasuku TOGASHIYFYuhei FujisawaYYYuya Yano

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Overview

Case report identifies lupus podocytopathy leading to nephrotic syndrome in systemic lupus erythematosus, highlighting diagnostic importance.

Key Points

  • To report a case of lupus podocytopathy as a renal manifestation in a patient with longstanding systemic lupus erythematosus.
  • Presented a case of a 28-year-old Japanese woman with a 12-year history of systemic lupus erythematosus (SLE)
  • Conducted laboratory studies revealing hypoalbuminemia and nephrotic-range proteinuria
  • Performed renal biopsy to assess for lupus nephritis class II
  • Identified lupus podocytopathy in the absence of prior renal involvement
  • Patient showed significant clinical improvement with corticosteroids and cyclophosphamide
  • Achieved near-complete resolution of proteinuria and maintained remission for six months

Cite This Study

TOGASHI et al. (2025) studied this question.

synapsesocial.com/papers/69253a29c0ce034ddc3576a2https://doi.org/10.1093/mrcr/rxaf072
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1O25 Lupus podocytopathy: a rare form of lupus nephritis – an Italian retrospective multicenter study2024
  2. 2Lupus podocytopathy with focal segmental glomerulosclerosis pattern and anti-neutrophil cytoplasmic antibody positivity: a case report2026
  3. 3Lupus podocytopathy: A systematic review of clinical evidence from cases and cohorts2026 · 2 citations
  4. 4Silent Storm: The Unfolding of Lupus Nephritis in a Young Female Patient2024 · 1 citations
  5. 5Clinical and morphological correlations in patients with lupus nephritis: a retrospective study2024