Practical Guidelines for the Prevention and Management of Diabetic Foot Disease in China

Diabetic foot (DF) is a prevalent and significant complication of diabetes mellitus. The primary factors that contribute to amputation and mortality in DF patients are multifaceted and include foot deformities, ulcers, ischemia, and potential concurrent infections. To further standardize DF prevention and treatment in China, improve consistency in DF diagnosis and treatment, and promote the development of a specialized tiered care system, the Chinese Burn Association (CBA), the Yangtze River Delta Integrated Diabetic Foot Alliance (YRD-DFA), and the Editorial Committee of the Chinese Journal of Burns and Wound Repair (Chin J Burns) established a multidisciplinary expert team. The team identified clinical issues concerning the diagnosis, treatment, and prevention of DF via the PICO framework, assessed the quality of relevant evidence using the GRADE system, and ultimately formulated a consensus titled ‘Practical Guidelines for the Prevention and Management of Diabetic Foot Disease in China’. The guidelines include 37 recommendations that address comprehensive medical assessment; internal medical treatments, including treatments related to blood glucose, blood pressure, and blood lipid control; antithrombotic and anti-infection therapy; perioperative risk assessment and management; surgical interventions, such as debridement, vascular reconstruction, and tissue repair; foot disease prevention; multidisciplinary collaboration; and the establishment of a hierarchical diagnosis and treatment system, with the objective of guiding clinical practice for managing DF in China.