Integration of a Novel Anti-PD-1 Antibody with CAR-T Engineered to Express IL-7 Enhances Targeting Efficacy against Lung Cancer

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1IL-7 armed binary CAR T cell strategy to augment potency against solid tumors2025 · 12 citations
2. 2Abstract 3999: Augmentation of antitumor effects by CAR-T cells secreting anti-PD-1 single-chain antibody fused with IL-212024
3. 3rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors2024 · 33 citations
4. 4Enhancement of CAR-T cell-targeted immune responses against solid tumors: role of lowered CARs affinity and addition of PD-1 chimeric antigen complexes2024
5. 5Abstract LB071: Weaponizing CAR T-cells to attack PD-L1 presenting cells in solid tumors2024