Analysis reveals potential biomarkers and hub genes linked to cryptorchidism, indicating roles in testicular development and injury.
This study identified a credible set of hub genes associated with cryptorchidism. Some of these genes have been shown to affect testicular development or spermatogenesis through mechanisms such as inflammation and oxidative stress, while others have not been fully studied in the context of cryptorchidism. These hub genes may provide new biomarkers for cryptorchidism risk assessment and warrant further investigation to clarify their specific roles.
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Huang et al. (2025) studied this question.
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