Preparation of Surface Molecularly Imprinted Polymer for BSA Using Cotton Fibers

The term molecularly imprinted polymers (MIPs) refers to a kind of polymer in which specific sites proportional to a particular species are created. The present study used cotton fibers to prepare an MIP for bovine serum albumin (BSA) protein on the surface of a polymer matrix. The results indicated that chloroform and acrylic acid had the best performance as solvents and functional monomers, respectively. The imprinting efficiency and the adsorption capacity of the BSA‐MIP were 2.93 and 316 mg/g, respectively. Contrast proteins (ovalbumin, insulin, and lysozyme) were also used to investigate the selectivity of the synthesized MIP. The selectivity factor of the BSA‐MIP compared to ovalbumin, lysozyme, and insulin protein was 1.77, 3.25, and 3.85, respectively. The results also showed that the Langmuir‐Freundlich isotherm model described the adsorption of BSA protein on the BSA‐MIP with a coefficient of determination of R 2 = 0.9986, which is better than the other isotherms.