What question did this study set out to answer?

This research aims to evaluate the implementation and outcomes of precision medicine through targeted therapy for pediatric brain tumors.

November 1, 2025Neuro-OncologyOpen Access

INNV-53. Precision Medicine in Pediatric Neuro-Oncology-Experience from a tertiary care center in Canada

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This research aims to evaluate the implementation and outcomes of precision medicine through targeted therapy for pediatric brain tumors.
Retrospective analysis of pediatric brain tumors diagnosed from 2010 to 2023
Included patients treated with at least one dose of targeted therapy
Evaluation of treatment modalities and associated outcomes
Forty patients treated with 50 lines of targeted therapy
Twenty patients commenced therapy based on molecular findings
Disease control rate of 78% with a clinical benefit rate of 63.3%

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Implication

Retrospective study reveals high clinical benefit rates with targeted therapy in pediatric neuro-oncology patients, indicating effective treatment options.

Cite This Study

Brizini et al. (2025) studied this question.

synapsesocial.com/papers/6925435ec0ce034ddc358163 https://doi.org/10.1093/neuonc/noaf201.0942

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Implication

Retrospective study reveals high clinical benefit rates with targeted therapy in pediatric neuro-oncology patients, indicating effective treatment options.

INNV-53. Precision Medicine in Pediatric Neuro-Oncology-Experience from a tertiary care center in Canada

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Discussion

Implication

Cite This Study

INNV-53. Precision Medicine in Pediatric Neuro-Oncology-Experience from a tertiary care center in Canada

Key Points

Discussion

Implication

Cite This Study

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