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November 1, 2025BMJ Digital Health & AIOpen Access

Responsible artificial intelligence in healthcare: a systematic review on the use of ethical principles in the development and deployment of artificial intelligence

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Authors

IIImane IhaddouchenSBStefan BuijsmanGPGiorgia Pozzi

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Overview

Systematic review highlights ethical principles guiding AI in clinical practice, suggesting improvements for responsible healthcare technology.

Key Points

  • Assess the integration of ethical principles in hospital-focused AI literature concerning the WHO guidelines.
  • Conducted a systematic review searching databases for studies on AI related to inpatient settings.
  • Included studies that referenced at least one WHO ethical principle.
  • Reviewed 4770 records, including 673 papers relevant to AI and ethics in healthcare.
  • Majority of included studies originated from high-income countries (83%).
  • 558 studies (83%) examined WHO ethical principles, notably focusing on inclusiveness and equity (49%).
  • Responsiveness and sustainability principles were rarely addressed (6%).

Cite This Study

Ihaddouchen et al. (2025) studied this question.

synapsesocial.com/papers/69254377c0ce034ddc358ae0https://doi.org/10.1136/bmjdhai-2025-000086
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