Case reports on cardiac MRI unveil Danon's disease in young adults with familial features, suggesting underdiagnosed conditions.
We report two cases of hypertrophic cardiomyopathy in young adults, both presenting with characteristic familial and clinical features, along with imaging abnormalities. Further evaluation revealed the underlying diagnosis to be Danon disease—an X‐linked dominant disorder caused by mutations in the LAMP‐2 gene. A comprehensive Medline search revealed a lack of published Indian literature specifically addressing Danon disease. Here, we present the clinical profiles and cardiac MRI findings of these two genetically confirmed cases.
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Goyal et al. (2025) studied this question.
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