Key result
Fibrotic biomarkers and abnormal P-wave indices are linked to incident AF in advanced HF.
Why the study?
Are fibrotic biomarkers and P-wave indices associated with incident atrial fibrillation in patients with advanced heart failure?
Are fibrotic biomarkers and P-wave indices associated with incident atrial fibrillation in patients with advanced heart failure?
Fibrotic biomarkers and abnormal P-wave indices are associated with the development of atrial fibrillation in patients with advanced heart failure, likely reflecting abnormal left atrial conduction.
In advanced HF patients, fibrotic biomarkers were associated with incident AF. Low P-wave and abnormal P-wave axis (<0 degree) were associated with incident AF. This may reflect abnormal LA-conduction pathway and displaced intra-atrial conduction pattern in advanced HF.
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Nezami et al. (2025) studied this question. Fibrotic biomarkers, low P-wave, and abnormal P-wave axis (<0 degree) were associated with incident atrial fibrillation in patients with advanced heart failure.
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